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LHRH-007A
Buserelin
Glp-His-Trp-Ser-Tyr-DSer(tBu)-Leu-Arg-Pro-NHEt
Size:1.0
P1(RMB):153
MW:1239.5
One letter sequence:Glp-HWSY-DSer(tBu)-LRP-NHEt
Molecular Formula:C60H86N16O13
Description:Buserelin is a longer acting synthetic peptide analog of the naturally occurring gonadotropin-releasing hormone (GnRH/LHRH). Substitution of glycine in position 6 by D-serine and that of glycinamide in position 10 by ethylamides produces a nonapeptide with higher LHRH effect. Buserelin's effect on FSH and LH release is approximately 20 to 170 times higher than those of natural LHRH.
Literature Reference:
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