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GLUC-008A
GLP-1/Glucagon-Like Peptide, human
His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Size:0.5
P1(RMB):582
MW:4169.6
One letter sequence:HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
Molecular Formula:C186H275N51O59
Description:GLP, synthesized by posttranslational processing of proglucagon in the intestine and pancreas, plays an important role in metabolic homeostasis. It is capable of converting intestinal epithelial cells into insulin-producing cells, thus serving as a new putative therapeutic compound for the treatment of diabetes mellitus.
Literature Reference:G.I. Bell et al., Nature, 304, 368 (1983)
Cas:[87805-34-3]