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CPEP-001A
C-Peptide, human
Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln
Size:0.5
P1(RMB):490
MW:3020.3
One letter sequence:EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
Molecular Formula:C129H211N35O48
Description:This C-peptide measurement can sensitively assess β-cell functions under standardized conditions, which is the most suitable primary outcome for clinical trials of therapies aimed at preserving or improving preserving endogenous insulin secretion in type 1 diabetes patients.
Literature Reference:A.S.C. Ko and D.G. Smyth, Eur. J. Biochem., 20, 190 (1971)\nP.E. Oyer et al., J. Biol. Chem., 246, 1375 (1971)\nK. Igano et al., Bull. Chem. Soc. Jpn., 54, 3088 (1981)
Cas:[33017-11-7]