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CASP-037B
FITC-C6-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)
FITC-C6-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)
Size:1.0
P1(RMB):368
MW:1431.48
One letter sequence:FITC-C6-YVADAP-Lys(Dnp)
Molecular Formula:C68H78N12O21S
Description:Specific substrate for the determination of caspase-1 and caspase-1-like enzyme activities. Cleavage of this peptide substrate at the P1 Asp residue causes a continuous fluorescent assay, thus useful both in FACS and fluorescence microscopy experiments. Caspase-3 is only weakly active on this substrate.
Literature Reference:H.J. Korting et al., Virologie, 28, 41 (1977); A. Chersi et al., Biochim. Biophys. Acta, 1034, 333 (1990)
Cas: