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CASP-035B
Caspase-1 Inhibitor V
Z-Val-Ala-DL-Asp(OMe)-FMK
Size:1.0
P1(RMB):521
MW:467.5
One letter sequence:Z-VA-DL-Asp(OMe)-FMK
Molecular Formula:C22H30F1N3O7
Description:ICE-like protease inhibitor that blocks all features of apoptosis: morphological changes, cleavage of caspase-3 (CPP32/Yama/Apopain) and poly(ADP-ribose) polymerase, lamin B degradation and DNA fragmentation.
Literature Reference:T. Shimizu et al., Leukemia, 11, 1238 (1997); H. Hara et al., Proc. Natl. Acad. Sci. USA, 94, 2007 (1997)
Cas: