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CASP-004A
Ac-WEHD-CHO
Ac-Trp-Glu-His-Asp-CHO
Ac-Trp-Glu-His-Asp-CHO
Size：1.0
P1(RMB)：153
MW：611.61
One letter sequence：Ac-WEHD-CHO
Molecular Formula：C28H33N7O9
Description：Very potent reversible inhibitor of caspase-1 (ICE) that contains the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM, it displays the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.
Literature Reference：T.A. Rano et al., Chem. Biol., 4, 149 (1997); M. Garcia-Calvo et al., J. Bio. Chem., 273, 32608 (1998)
Cas：[189275-71-6]
P1(RMB)：153
MW：611.61
One letter sequence：Ac-WEHD-CHO
Molecular Formula：C28H33N7O9
Description：Very potent reversible inhibitor of caspase-1 (ICE) that contains the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM, it displays the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.
Literature Reference：T.A. Rano et al., Chem. Biol., 4, 149 (1997); M. Garcia-Calvo et al., J. Bio. Chem., 273, 32608 (1998)
Cas：[189275-71-6]
