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ATMP-005B
Dermaseptin
Ala-Leu-Trp-Lys-Thr-Met-Leu-Lys-Lys-Leu-Gly-Thr-Met-Ala-Leu-His-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Ala-Ala-Asp-Thr-Ile-Ser-Gln-Gly-Thr-Gln
Size:1.0
P1(RMB):1195
MW:3455.1
One letter sequence:ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
Molecular Formula:C152H257N43O44S2
Description:Peptide that is isolated from skin extracts of the South American arboreal frog, Phyllomedusa Sauvagei. It is a strongly basic, water-soluble, thermalstable nonhemolytic compound, nonhemolytic peptide that exhibits highly potent antimicrobial activity against pathogenic fungi at micromolar concentration. A potential amphiphatic α-helix structure can probably function by membrane permeabilization.
Literature Reference:A. Mor et al., Biochemistry, 30, 8824 (1991)
Cas: