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GUAN-001A
Guanylin, human
Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys(Cys4&Cys12 bridge , Cys7&Cys15 bridge)
Size:0.5
P1(RMB):766
MW:1458.7
One letter sequence:PGTCEICAYAACTGC (C4&C12 bridge , C7&C15 bridge)
Molecular Formula:C58H87N15O21S4
Description:Intestinal guanylate cyclase activator that is isolated from rat intestine and activates intestinal guanylate cyclase in a human colon carcinoma-derived cell line (T84). It resembles heat-stable endotoxins produced by E. coli.
Literature Reference:R.C. Wiegand et al., FEBS Letters, 311, 150 (1992)
Cas: