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UROT-003B
Urotensin II , human
Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val(Cys5&Cys10 bridge)
Size:1.0
P1(RMB):582
MW:1388.59
One letter sequence:ETPDCFWKYCV(Cys5&Cys10 bridge)
Molecular Formula:C64H85N13O18S2
Description:A vasoactive \"somatostatin-like\" cyclic peptide originally derived from fish spinal cords that has recently been cloned from man. It was found to be the most potent mammalian vasoconstrictor identified so far and may have additional activities, as urotensin II immunoreactivity was also found within the central nervous system and endocrine tissues.
Literature Reference:Y. Coulouarn at al., Proc. Natl Acad. Sci. USA, 95, 15803 (1998); R.S. Ames et al., Nature, 401, 282 (1999)
Cas: