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PPEP-004
ε-V1-2, ε-PKC Inhibitor
Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr
Size:1
P1(RMB):275
MW:844
One letter sequence:EAVSLKPT
Molecular Formula:
Description:This peptide is derived from residues 14-21 of protein kinase C C2 (εPKC C2). This peptide specifically inhibits εPKC by disrupting PKC binding to its receptor, RACK2. εPKC mediated signal transduction plays a role in cell proliferation, differentiation, and apoptosis.
Literature Reference:Lamy, C. et al. Tetrahedron Lett 46, 6177 (2007)\nBrandman, R. et al. J. Biol. Chem. 282, 4113 (2007)
Cas: