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PACA-009B
PACAP (6-38), amide, human, ovine, rat
Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
Size:1
P1(RMB):851
MW:4024.8
One letter sequence:FTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
Molecular Formula:C182H300N56O45S
Description:This peptide is a potent antagonist of PACAP 38 and is much more potent and selective than PACAP (6-27) in the inhibition of PACAP-27 stimulated pituitary adenylate cyclase. The Ki values for the inhibition of the enzyme are 7nM and 150 nM, respectively.
Literature Reference:Robberecht, P. et al. Eur. J. Biochem. 207, 239 (1992)\nP. Robberechtet al. Eur. J. Biochem., 207, 239 (1992)\nA. Vandermeers, et al. Eur. J. Biochem., 208, 815 (1992)
Cas: