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AMYN-006A
Amylin, human amidated
Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2(Cys2&Cys7 bridge)
Size:0.5
P1(RMB):766
MW:3905.4
One letter sequence:KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2 (C2&C7 bridge)
Molecular Formula:C165H263N51O55S2
Description:37 amino acid polypeptide secreted from the β cells of the pancreas and structurally related to calcitonin. It has anorectic effects in rats and may be responsible for the etiology of insulin resistance of type II diabetes mellitus through its modulation of peripheral effects of insulin. It blocks the activation of glycogen synthase by insulin.
Literature Reference:
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