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PARP-005B
PAR-2 (1-6) (mouse, rat)
Ser-Leu-Ile-Gly-Arg-Leu-OH\nTrifluoroacetate salt
Size:25
P1(RMB):2700
MW:657.81
One letter sequence:SLIGRL
Molecular Formula:C29H55N9O8
Description:This peptide is the tethered ligand sequence of mouse PAR-2, which like the thrombin receptor is a protease-activated receptor present in keratinocytes. This peptide was found to be equipotent with SFLLRN in activating keratinocyte inositolphospholipid hydrolysis and calcium mobilization.
Literature Reference:R.J.Santulli et al., Proc. Natl. Acad. Sci. USA, 92, 9151 (1995)\nA. Bhattacharya et al., J. Pharmacol. Exp. Ther., 297, 573 (2001).\nB. Al-Ani, et al., J. of Physiol. Pharmacol., 73, 1203 (1995).
Cas:164081-25-8