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METO-001A
Metorphamide
Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2
Size:1
P1(RMB):198
MW:984.19
One letter sequence:YGGFMRRV-NH2
Molecular Formula:C44H69N15O9S
Description:This peptide is the C-terminally amidated octapeptide found in bovine brain and adrenal tissue, corresponds to residues 206-213 of the bovine proenkephalin precursor. It is also related in sequence to the bovine adrenal medulla peptides. So far, it is the only endogenous opioid peptide with high affinity for μ opioid receptors.
Literature Reference:H.Matsuo et al., Nature, 305, 721 (1983)\nE.Weber et al., Proc. Natl. Acad. Sci. USA, 80, 7362 (1983)\nP.D.Marley et al., Brain Res., 363, 10 (1986)\nM.Sonders and E.Weber, J. Neurochem., 49, 671 (1987)
Cas:88377-68-8