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GRFF-009A
SPARC (119-122) (mouse)
H-Lys-Gly-His-Lys-OH\nAcetate salt
Size:50
P1(RMB):606
MW:468.56
One letter sequence:KGHK
Molecular Formula:C20H36N8O5
Description:SPARC is a transiently expressed extracellular matrix-binding protein that alters cell shape and regulates endothelial cell proliferation in vitro. KGHK , a copper-binding peptide fragment, has been shown to be a potent stimulator of angiogenesis. Specific degradation of SPARC by proteases of the extracellular fluid may release this bioactive peptide.
Literature Reference:T.F.Lane et al., J. Cell Biol., 125, 929 (1994)
Cas:155149-79-4