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HIST-079A
AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTYSFGHHA]
H-Ala-Arg-Lys-Arg-Glu-Arg-Thr-Tyr-Ser-Phe-Gly-His-His-Ala-OH
Size:1
P1(RMB):425
MW:1715.9
One letter sequence:ARKRERTYSFGHHA
Molecular Formula:
Description:The native peptide ARKRERTYSFGHHA is a synthetic substrate for AKT/PKB/Rac-protein kinases. Phophorylation is at the Ser site (Km = 3.9 μM). It also competitively inhibits histone H2B phosphorylation (Ki = 12 μM) by AKT.
Literature Reference:Ref: Obata, T. et al. J. Biol. Chem. 275, 36108 (2000). Chan, TO. et al. Ann. Rev. Biochem. 68, 965 (1999).
Cas: