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MOG-002B
Myelin Oligodendrocyte Glycoprotein (35-55) (human)\nMOG (35-55) (human)
H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Pro-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH\nTrifluoroacetate salt
Size:1
P1(RMB):560
MW:2592.03
One letter sequence:MEVGWYRPPFSRVVHLYRNGK-OH
Molecular Formula:C120H179N35O28S
Description:In contrast to the encephalitogenic rat homolog, this peptide is not a major T-cell epitope in multiple sclerosis propably due to its lower amount of helical structure formed when dissolved in micellar sodium dodecyl sulfate. This peptide induced anti-MOG(35-55) autoantibody production in C57BL/6 mice.
Literature Reference:N.Kerlero de Rosbo et al., Eur. J. Immunol., 27, 3059 (1997)\nS.Albouz-Abo et al., Eur. J. Biochem., 246, 59 (1997)\nM.F.Mesleh et al., Neurobiol. Dis., 9, 160 (2002)\nOliver, A. J. Immunology 171, 462 (2003)\nStromnes, I. et al. Nature protocols 1, 1810 (2006)
Cas:163158-19-8