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SUBP-003B
Spantide II
DLys(Nicotinoyl)-Pro-(3-Pyridyl)Ala-Pro-(3,4-dichloro)DPhe-Asn-DTrp-Phe-DTrp-Leu-Nle-NH2
Size:1.0
P1(RMB):490
MW:1670.8
One letter sequence:DLys(Nicotinoyl)-P-(3-Pyridyl)Ala-P-(3,4-dichloro)DPhe-N-DTrp-F-DTrp-L-Nle-NH2
Molecular Formula:C86H106N18O13Cl2
Description:Tachykinin antagonist that is a more potent substance P antagonist than spantide I and less effective in releasing histamine from mast cells. It also displays negligible neurotoxicity when compared with spantide I.
Literature Reference:Folkers et al., PNAS, 87, 4833 (1990); \nR. Kakanson et al., BBRC, 178, 297 (1991)
Cas: