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PACA-004B
PACAP (1-27), human, ovine, rat
His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2
Size:1.0
P1(RMB):1011
MW:3147.7
One letter sequence:HSDGIFTDSYSRYRKQMAVKKYLAAVL-NH2
Molecular Formula:C142H224N40O39S1
Description:PACAP-38 and its N-terminal fragment PACAP-27 are novel neuropeptides originally isolated from bovine hypothalamus. They are also found in humans and rats. Both PACAP-27 and PACAP-38, showing considerable homology with vasoactive intestinal polypeptide (VIP), can stimulate adenylate cyclase much more potently than VIP.
Literature Reference:A. Miyata et al., BBRC, 164, 567 (1989); \nA. Mirata et al., Regulatory Peptides, 26, 170 (1989)
Cas: