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CANC-016A
p53 (17-26)
Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu
Size:1mg
P1(RMB):275
MW:1251.5
One letter sequence:ETFSDLWKLL
Molecular Formula:
Description:This peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2. The tumor suppressor protein p53 is important in maintaining genome stability and in preventing cancer development.
Literature Reference:Wang, Y. et al. J. Biol. Chem. 281, 24803 (2006) Kanovsky, M. et al. PNAS 98, 12438 (2001).
Cas: